At Dextrose Technologies Pvt. Ltd., we offer Headspace GCMS (HS-GCMS) testing for accurate analysis of volatile compounds with reduced matrix interference. By sampling the vapor phase above the sample, HS-GCMS improves repeatability for residual solvent testing, volatile impurity profiling, and screening studies. Our workflows are designed for R&D and QC support with clean documentation and decision-ready reporting. Residual Solvent Analysis (ICH Q3C-Oriented) We support ICH Q3C-oriented residual solvent analysis by targeting relevant solvents, using calibration-based quantification (as applicable), and reporting results in clear units based on your limits and sample type. Volatile Impurity Profiling We profile unknown or suspected volatile impurities to support troubleshooting, process optimization, and batch comparison, with MS-based confirmation where possible. Packaging Interaction Studies (Screening) We provide screening studies to evaluate potential volatile compounds that may arise from packaging/contact materials interactions (scope-dependent), useful for early risk assessment and comparison between packaging options. Stability Study Support for Volatile Components We support stability programs by tracking volatile components across timepoints, enabling trend analysis and comparison between storage conditions or formulations. Deliverables * Headspace GCMS chromatograms + peak tables * Mass spectra and identification summary (where applicable) * Quantitative results (when standards/targets and reporting limits are defined) * Method notes and interpretation aligned to your objective * Optional recommendations for follow-up confirmation or expanded screening Get started Share your sample type, target solvent list (if known), required limits/units, and whether you need ID only or ID + quantification. We’ll propose the right HS-GCMS workflow.